Department of Ecogenetics and Systems Biology - Division of Archaea Biology and Ecogenomics


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Schleper

People > Staff

Univ.-Prof. Dipl.-Biol. Dr. Christa Schleper
Vice-Head of Department

Room: 1.093
Wien, Althanstraße 14 (UZA I)
T: +43-1-4277-76510
M: +43-664-60277-76510
F: +43-1-4277-876510
christa.schleper(at)univie.ac.at


CURRICULUM VITAE

PERSONAL DETAILS

Title

University Professor

Download CV

Citizenship

german

Download full list of publications

   

RESEARCH INTERESTS

1.) Ecology, genetics and evolution of Archaea
with a focus on

- stress reactions, virus-host interactions and RNA-Interference in hyperthermophilic Archaea
- metabolism and ecology of moderate and extremophilic ammonia oxidizing archaea

2.) Metagenomics

Development and application of metagenomic and metatranscriptomic approaches to study natural microbial communities with a focus on terrestrial and arctic environments

   

APPOINTMENTS/CAREER

04/2013 - now

Vice-Head of Department Ecogenomics and Systems Biology, University of Vienna Austria
Archaea Biology and Ecogenomics Group Leader
our department "Genetics in Ecology" has fused with the department "Molecular Systems Biology"

10/2007 - 03/2013

Head of Department Genetics in Ecology, University of Vienna, Austria

2007 - 2014

Adjunct Professor,Center of Excellence for Geobiology, University of Bergen, Norway

2004 - 2007

University Professor, Department of Biology, University of Bergen, Norway

1998 - 2004

Group leader ("assistant professor") at the University of Darmstadt, Germany at the Institute of Microbiology and Genetics

04/2002

Habilitation, venia legendi for teaching in Microbiology and Genetics (University of Darmstadt, Germany)

1996 - 1997

University of California Santa Barbara (UCSB)
Postdoctoral fellow in the laboratory of Dr. Edward DeLong

1996

Californian Institute of Technology, Pasadena and Agouron Institute, La Jolla, CA
Postdoctoral fellow with Dr. Melvin Simon

1994 - 1995

Max-Planck-Institute for Biochemistry, Martinsried, Germany
Postdoctoral fellow in the laboratory of Dr. Wolfram Zillig

1989 - 1993

Max-Planck-Institute for Biochemistry, Martinsried, Germany
Doctorate (PhD) in the laboratory of Dr. Wolfram Zillig

   

EDUCATION

1988 - 1989

Diploma in Biology, University of Konstanz, Germany

1986 - 1988

University of Konstanz, Germany
Studies in biology: microbiology, immunology and genetics

1982 - 1985

University of Aachen, Germany
Studies in biology, sociology and languages (english, french)

   

HONORS/AWARDS

04/2013

Corresponding member of the Austrian Academy of Sciences

02/2012

Elected member of the American Academy of Microbiology

05/2011

EMBO Young Investigator Award 2000 (EMBO - YIP)

1955 - 1997

Post-Doctoral Fellowship of the Deutsche Forschungsgemeinschaft

   

PATENTS

US Patent

„Nucleic Acids and Proteins from the uncultivated Archaeon Cenarchaeum symbiosum“

(WO200018909-A)

EU Patent

“Expression vectors for hyperthermophilic Archaea"

(WO2004106527-A1)

EU Patent

“Isolation and cloning of DNA from uncultivated microorganisms“

(WO2004018673-A2)

   

ACTIVITIES(selected)

2013 - now

Member of the Commission for Interdisciplinary Ecological Studies (KIÖS) of the Austrian Academy of Sciences (ÖAW)

2013

Evaluation panel for Leibniz Institute DSMZ (German Collection of Microorganisms and Cell Cultures)

2011 - 2012

Senior Editor of ISME Journal

2011

Co-Editor of special issue on Archaea in: Current Opinion in Microbiology
Co-Editor of 2 special issues "METAGENOMICS" in: Environmental Microbiology

2009 - 2012

Main Coordinator of INFLAMMOBIOTA: Metagenomics and Metatranscriptomics of the Inflammatory Bowel Disease Microbiota. National consortium funded by the Austrian Genome Programme GEN-AU.

2008 - now

Member of the editorial board of: Environmental Microbiology

2007 - 2010

Main Coordinator of the international Era-Net project: SulfoSYS (Silicon Cell Model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation) within SysMO (Systems Biology of Microorganisms)

09/2007

Co-organizer of the International meeting: Thermophiles 2007. Bergen, Norway

06/2005

Co-organizer of the International meeting: Archaea, the first generation, to the honor of Karl-Otto Stetter and Wolfram Zillig. München, Germany

06/2003

Main organizer (scientific and logistics) of the International Workshop: Metagenomics 2003: From Microbial Diversity to Function. Darmstadt, Germany

11/2001

Co-organizer of the Symposium: Arbeitsfeld Biowissenschaften: Lebenswege von Naturwissenschaftlerinnen. University of Technology Darmstadt, Germany

2000 - 2001

Co-organizer of an International seminar series: Women in Biosciences. University of Technology, Darmstadt, Germany

   

MENTORING

2011

Mentor of the Mentoring Programm at the University of Vienna (muv5) for female senior postdocs
Mentor in CyberMint for highschool girls interested in natural sciences

1998 - 2004

Mentor in the Women Mentoring Program for students, Frankfurt-Darmstadt, Germany

   

MEMBERSHIPS

Commission for Interdisciplinary Ecological Studies (KIÖS) of the Austrian Academy of Sciences (ÖAW)

International Society of Microbial Ecology (ISME)
Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM)
American Society for Microbiology (ASM)
Austrian Association of Molecular Life Sciences and Biotechnology (ÖGMBT)

   

INVITED INTERNATIONAL CONFERENCE LECTURES (2008-now, selection)

Invited Lecture

CRISPR-mediated Virus Defense in the Hyperthermophilic Archaeon Sulfolobus solfataricus. 05/2014. 3rd European CRISPR Meeting, Berlin, Germany.

Invited Lecture & Session convenor

The Archaeon among Us: Thaumarchaeota and Others that Affect Our Daily Life. 05/2014. American Society of Microbiology Annual Meeting, Boston, USA.

Invited Lecture

Genomic and phenotypic characterization of Thaumarchaeota from soil. 05/2014. Molecular Biology of Archaea 4 (MBoA4) Paris, France.

Invited Keynote Lecture

Physiology and Ecology of arctic Thaumarchaeota. 09/2013. ICoN3: Third International Conference on Nitrification. Tokyo, Japan.

Invited Plenary Lecture

Ammonia Oxidizing Archaea: Ecology and Evolution. 03/2013. VAAM and Joint conference of the German and Dutch Societies for Microbiology. Bremen, Germany.

Invited Plenary Lecture

Physiology of Thaumarchaeota: Testing Genomic Predictions on a Pure Culture. 07/2012. Molecular Biology of Archaea 3. Marburg, Germany.

Invited Keynote Lecture

Ammonia oxidizing Archaea from Soil: Discovery of an old Group. 04/2011. Ecology of Soil microorganisms. Prague, Czech Republic.

Invited Keynote Lecture

Thaumarchaeota: Their Lifestyles and Evolution. 08/2011. Gordon Research Conference: Archaea: Ecology, Metabolism and Molecular Biology. Waterville Valley, New Hampshire, USA.

Invited Plenary Lecture

Thaumarchaeota: Testing (meta)genomic predictions on a pure culture. 10/2011. Jaques Monod Conference: Integrative ecological genomics. Roscoff, France.

Invited Plenary Lecture

In vivo activity of CRISPR mediated virus defense in the hyperthermophilic archaeon Sulfolobus solfataricus. 08/2010. Gordon Research Conference: Archaea: Ecology, Metabolism and Molecular Biology. 07/2009, Waterville Valley, New Hampshire, USACRISPR Mechanisms & Applications, Wageningen, The Netherlands.

Invited Plenary Lecture

Genomics of the novel Phylum Thaumarchaeota. 08/2010. Molecular biology of Archaea II Conference. Robinson College, Cambridge, UK.

Invited Keynote Lecture

Evolution and Physiology of Ammonia Oxidizing Archaea. 08/2010. 13th International Symposium on Microbial Ecology, Seattle, USA.

Invited Plenary Lecture

Ecophysiology and Evolution of Ammonia-Oxdizing Archaea. 07/2009. Gordon Research Conference: Archaea: Ecology, Metabolism and Molecular Biology. Waterville Valley, New Hampshire, USA.

Invited Plenary Lecture

Metagenomics of ammonia oxidizing archaea from soils and hot springs. 07/2009. ICoN1: First International Conference on Nitrification. Louisville Kentucky, USA.

Invited Session Co-Convenor Speaker

Metagenomics and -transcriptomics of Ammonia oxidizing Archaea. 06-07/2009. FEMS: 3rd Congress of European Microbiologists. Göteborg, Sweden.

Invited Keynote Lecture

Ecology and Evolution of Ammonia oxidizing Archaea. 06/2009. International Conference BAGECO 10: Bacterial Genetics and Ecology – Coexisting on a Changing Planet. Uppsala, Sweden.

Invited Plenary Lecture

Responses of the hyperthermophilic archaeon Sulfolobus solfataricus to UV irradiation. 08/2008. Biochemistry of Archaea – Molecular Biology of Archaea. St.Andrews, Scotland.

Invited Plenary Lecture

Simultaneous assessment of soil microbial community structure and function using metatranscriptomics. 06/2008. EMBO Workshop: Microbial diversity and Metagenomics. Chalkid, Greece.

Invited Plenary Lecture

Metagenomics of ammonia oxidizing Archaea. 05/2008. Workshop of the Dutch Academy of Sciences: Assessing marine microbial diversity: Problems and solutions. Amsterdam, The Netherlands.

MOST IMPORTANT PUBLICATIONS

  • Spang A, Saw JH, Jørgensen SL, Zaremba-Niedzwiedzka K, Martijn J, Lind AE, van Eijk R, Schleper C, Guy L, Ettema TJ (2015) Complex archaea that bridge the gap between prokaryotes and eukaryotes. Nature 521(7551): 173-179. doi:10.1038/nature14447
  • Stieglmeier M, Mooshammer M, Kitzler B, Wanek W, Zechmeister-Boltenstern S, Richter A, Schleper C (2014) Aerobic nitrous oxide production through N-nitrosating hybrid formation in ammonia-oxidizing archaea. ISME Journal 8(5): 1135-1146.
  • Zebec Z, Manica A, Zhang J, White M, Schleper C (2014) CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricus. Nucleic Acids Research 42(8): 5280-5288.
  • Manica A, Zebec Z, Steinkellner J, Schleper C (2013) Unexpectedly broad target recognition of the CRISPR-mediated virus defence system in the archaeon Sulfolobus solfataricus. Nucleic Acids Research 41(22): 10509-10517.
  • Albers SV, Forterre P, Pranighvili D, Schleper C (2013) The legacy of Carl Woese and Wolfram Zillig: from phylogeny to landmark discoveries. Nature Reviews Microbiology 11: 713-719.
  • Offre P, Spang A, Schleper C (2013) Archaea in Biogeochemical Cycles. Annual Review of Microbiology 67: 437-457. Reproduced with permission from the Annual Review of Microbiology, Volume 67 (c) 2013 by Annual Reviews. Download
  • Manica A, Schleper C (2013) CRISPR-mediated defense mechanisms in the hyperthermophilic archaeal genus Sulfolobus. RNA Biology 10(5): 671-678.
  • Alves RJ, Wanek W, Zappe A, Richter A, Svenning MM, Schleper C, Urich T (2013) Nitrification rates in Arctic soils are associated with functionally distinct populations of ammonia-oxidizing archaea. ISME Journal 7(8): 1620-1631.
  • Spang A, Poehlein A, Offre P, Zumbrägel S, Haider S, Rychlik N, Nowka B, Schmeisser C, Lebedeva EV, Rattei T, Böhm C, Schmid M, Galushko A, Hatzenpichler R, Weinmaier T, Daniel R, Schleper C, Spieck E, Streit W, Wagner M (2012) The genome of the ammonia-oxidizing Candidatus Nitrosopshaera gargensis: Insights into metabolic versatility and environmental adaptations. Environmental Microbiology 14(12): 3122-3145.
  • Jørgensen S, Hannisdal B, Lanzen A, Baumberger T, Flesland K, Fonseca R, Ovreas L, Steen IH, Torseth IH, Pedersen RB, Schleper C (2012) Correlating microbial community profiles with geochemical data in highly stratified sediments from the Arctic Mid-Ocean Ridge. Proceedings of the National Academy of Sciences of the United States of America 109(42): E2846-E2855.
  • Ajon M, Fröls S, van Wolferen M, Stoecker K, Teichmann D, Driessen AJM, Grogan DW, Albers SV, Schleper C (2011) UV-inducible DNA exchange in hyperthermophilic archaea mediated by type IV pili. Molecular Microbiology 82(4): 807-817.
  • Tourna M, Stieglmeier M, Spang A, Könneke M, Schintlmeister A, Urich T, Engel M, Schloter M, Wagner M, Richter A, Schleper C (2011) Nitrososphaera viennensis, an ammonia oxidizing archaeon from soil. Proceedings of the National Academy of Sciences of the United States of America 108(20): 8420-8425.
  • Schleper C, Nicol GW (2010) Ammonia-oxidising archaea-physiology, ecology and evolution. Advances in Microbial Physiology 57: 1-47.
  • Spang A, Hatzenpichler R, Brochier-Armanet C, Rattei T, Tischler P, Spieck E, Streit W, Stahl DA, Wagner M, Schleper C (2010) Distinct gene set in two different lineages of ammonia-oxidizing archaea supports the phylum Thaumarchaeota. Trends in Microbiology 18(8): 331-340.
  • Schauss K, Focks A, Leininger S, Kotzerke A, Heuer H, Thiele-Bruhn S, Sharma S, Wilke BM, Matthies M, Smalla K, Munch JC, Amelung W, Kaupenjohann M, Schloter M, Schleper C (2009) Dynamics and functional relevance of ammonia-oxidizing archaea in two agricultural soils. Environmental Microbiology 11(2): 446-456.
  • Leininger S, Urich T, Schloter M, Schwark L, Qi J, Nicol G, Prosser J, Schuster S, Schleper C (2006) Archaea predominate among ammonia-oxidizing prokaryotes in soils. Nature 442(7104): 806-809.
  • Treusch A, Leiniger S, Kletzin A, Schuster S, Klenk H, Schleper C (2005) Novel genes for nitrite reductase and Amo-related proteins indicate a role of uncultivated mesophilic crenarchaeota in nitrogen cycling. Environmental Microbiology 7(12): 1985-1995.
  • Schleper C, Puhler G, Kuhlmorgen B, Zillig W (1995) Life at extremely low pH. Nature 375(6534):741-742.
  • Schleper C, Kubo K, Zillig W (1992) The Particle SSV1 from the extremely thermophilic Archaeon Sulfolobus is a virus - demonstration of infectivity and of transfection with viral-DNA. Proceedings of the National Academy of Sciences of the United States of America 89(16): 7645-7649.

Full list of publications

2016

  • Wild B, Gentsch N, Capek P, Diakova K, Alves RJE, Barta J, Gittel A, Hugelius G, Knoltsch A, Kuhry P, Lashchinskiy N, Mikutta R, Palmtag J, Schleper C, Schnecker J, Shibistova O, Takriti M, Torsvik V, Urich T, Watzka M, Santruckova H, Guggenberger G, Richter A (2016) Plant-derived compounds stimulate the decomposition of organic matter in arctic permafrost soils. Scientific Reports 6: 25607doi:10.1038/srep25607.
  • Nesme J, Achouak W, Agathos S, Bailey M, Baldrian P, Brunel D, Frostegård Å, Heulin T, Jansson J, Jurkevitch E, Kruus K, Kowalchuk G, Lagares A, Lappin-Scott H, Lemanceau P, Le Paslier D, Mandic-Mulec I, Murrell JC, Myrold D, Nalin R, Nannipieri P, Neufeld JD, O'Gara F, Parnell JJ, Pühler A, Pylro V, Ramos JL, Roesch L, Schloter M, Schleper C, Sczyrba A, Sessitsch A, Sjöling S, Sørensen J, Sørensen S, Tebbe C, Topp E, Tsiamis G, van Elsas JD, van Keulen G, Widmer F, Wagner M, Zhang T, Zhang X, Zhao L, Zhu Y-G, Vogel T, Simonet P (2016) Back to the Future of Soil Metagenomics. Frontiers in Microbiology 7:73. doi: 10.3389/fmicb.2016.00073.
  • Söllinger A, Schwab C, Weinmaier T, Loy A, Tveit AT, Schleper C, Urich T (2015) Phylogenetic and genomic analysis of Methanomassiliicoccales in wetlands and animal intestinal tracts reveals clade-specific habitat preferences. FEMS Microbiology Ecology 92(1). doi: 10.1093/femsec/fiv149.


2015

  • Taubner RS, Schleper C, Firneis MG, Rittmann SK (2015) Assessing the Ecophysiology of Methanogens in the Context of Recent Astrobiological and Planetological Studies. Life (Basel) 5(4):1652-86. doi: 10.3390/life5041652.
  • Berry D, Kuzyk O, Rauch I, Heider S, Schwab C, Hainzl E, Decker T, Müller M, Strobl B, Schleper C, Urich T, Wagner M, Kenner L, Loy A (2015) Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis. Frontiers in Microbiology 6:1408. doi: 10.3389/fmicb.2015.01408.
  • Bayer B, Vojvoda J, Offre P, Alves RJE, Elisabeth NH, Garcia JA, Volland JM, Srivastava A, Schleper C, Herndl GJ (2015) Physiological and genomic characterization of two novel marine thaumarchaeal strains indicates niche differentiation. The ISME Journal, 2015 Nov 3. [Epub ahead of print]
  • Hainzl E, Rauch I, Heider S, Berry D, Schwab C, Lassnig C, Loy A, Urich T, Wagner M, Schleper C, Kenner L, Decker T, Strobl B, Müller M (2015) Intestinal epithelial cell tyrosine kinase 2 transduces interleukin-22 signals to protect from acute colitis. The Journal of Immunology 195(10): 5011-5024.
  • Capek P, Diakova K, Dickopp JE, Bárta J, Wild B, Schnecker J, Alves RJE, Aiglsdorfer S, Guggenberger G, Gentsch N, Hugelius G, Lashchinskiy N, Gittel A, Schleper C, Mikutta R, Palmtag J, Shibistova O, Urich T, Richter A, Šantrùèková H. (2015). The effect of warming on the vulnerability of subducted organic carbon in arctic soils. Soil Biology & Biochemistry 90: 19-29.
  • Spang A, Saw JH, Jørgensen SL, Zaremba-Niedzwiedzka K, Martijn J, Lind AE, van Eijk R, Schleper C, Guy L, Ettema TJ (2015) Complex archaea that bridge the gap between prokaryotes and eukaryotes. Nature 521(7551): 173-179. doi:10.1038/nature14447.
  • Taylor AE, Taylor K, Tennigkeit B, Palatinszky M, Stieglmeier M, Myrold DD, Schleper C, Wagner M, Bottomley PJ (2015) Inhibitory effects of c2 to c10 1-alkynes on ammonia oxidation in two nitrososphaera species. Applied and environmental microbiology 81(6): 1942-1948. doi: 10.1128/AEM.03688-14.


2014

  • Gittel A, Barta J, Lacmanova I, Schnecker J, Wild B, Capek P, Kaiser C, Torsvik V, Richter A, Schleper C, Urich T (2014) Site- and horizon-specific pattern of microbial community structure and enzyme activities in permafrost-affected soils of Greenland. Frontiers in Microbiology - Terrestrial Microbiology. doi: 10.3389/fmicb.2014.00541.
  • Offre P, Kerou M, Spang A, Schleper C (2014) Variability of the transporter gene complement in ammonia-oxidizing archaea. Trends in Microbiology. doi: 10.1016/j.tim.2014.07.007.
  • Rauch I, Hainzl E, Rosebrock F, Heider S, Schwab C, Berry D, Stoiber D, Wagner M, Schleper C, Loy A, Urich T, Müller M, Strobl B, Kenner L, Decker T (2014) Type I interferons have opposing effects during the emergence and recovery phases of colitis. European Journal of Immunology. doi: 10.1002/eji.201344401.
  • Stieglmeier M, Klingl A, Alves RJ, Rittmann SK, Melcher M, Leisch N, Schleper C (2014) Nitrososphaera viennensis sp. nov., an aerobic and mesophilic ammonia-oxidizing archaeon from soil and member of the archaeal phylum Thaumarchaeota. International Journal of Systematic and Evolutionary Microbiology. 2014 Jun 28. doi: 10.1099/ijs.0.063172-0.
  • Hanak AM, Nagler M, Weinmaier T, Sun X, Fragner L, Schwab C, Rattei T, Ulrich K, Ewald D, Engel M, Schloter M, Bittner R, Schleper C, Weckwerth W (2014) Draft Genome Sequence of the Growth-Promoting Endophyte Paenibacillus sp. P22, Isolated from Populus. Genome Announcements 2(2): e00276-14.
  • Urich T, Lanzén A, Stokke R, Bayer C, Pedersen RB, Thorseth I, Schleper C, Steen IH, Øvreas L (2014) Microbial community structure and functioning in marine sediments associated with diffuse hydrothermal venting assessed by integrated meta-omics. Environmental Microbiology. doi: 10.1111/1462-2920.12283.
  • Gittel A, Bárta J, Kohoutová I, Mikutta R, Owens S, Gilbert J, Schnecker J, Wild B, Hannisdal B, März J, Lashchinskiy N, Èapek P, Šantrùèková H, Gentsch N, Shibistova O, Guggenberger G, Richter A, Torsvik V, Schleper C, Urich T (2014) Distinct microbial communities associated with buried soils in the Siberian tundra. Journal of Systematic and Evolutionary Microbiology 8: 841-853.
  • Schwab C, Berry D, Rauch I, Rennisch I, Ramesmayer J, Hainzl E, Heider S, Decker T, Kenner L, Müller M, Strobl B, Wagner M, Schleper C, Loy A, Urich T (2014) Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery. Journal of Systematic and Evolutionary Microbiology 8: 1101-1114.
  • Schwab C, Tveit A, Schleper C, Urich T (2014) Gene expression of lactobacilli in murine forestomach biofilms. Microbial Biotechnology 7(4): 347-359.
  • Stieglmeier M, Mooshammer M, Kitzler B, Wanek W, Zechmeister-Boltenstern S, Richter A, Schleper C (2014) Aerobic nitrous oxide production through N-nitrosating hybrid formation in ammonia-oxidizing archaea. Journal of Systematic and Evolutionary Microbiology 8(5): 1135-1146.
  • Zebec Z, Manica A, Zhang J, White M, Schleper C (2014) CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricus. Nucleic Acids Research 42(8): 5280-5288.
  • Prommer J, Wanek W, Hofhansl F, Trojan D, Offre P, Urich T, Schleper C, Sassmann S, Kitzler B, Soja G, Hood-Nowotny R (2014) Biochar Decelerates Soil Organic Nitrogen Cycling but Stimulates Soil Nitrification in a Temperate Arable Field Trial. PLOS One 9(1): e86388.


2013

  • Manica A, Zebec Z, Steinkellner J, Schleper C (2013) Unexpectedly broad target recognition of the CRISPR-mediated virus defence system in the archaeon Sulfolobus solfataricus. Nucleic Acids Research 41(22): 10509-10517.
  • Jorgensen S, Thorseth I, Pedersen R, Baumberger T, Schleper C (2013) Quantitative and phylogenetic study of the Deep Sea Archaeal Group in sediments of the Arctic mid-ocean spreading ridge. Frontiers in Microbiology 4: 299.
  • Alves R, Wanek W, Zappe A, Richter A, Svenning M, Schleper C, Urich T (2013) Nitrification rates in Arctic soils are associated with functionally distinct populations of ammonia-oxidizing archaea. ISME Journal 7(8): 1620-1631.
  • Shen T, Stieglmeier M, Dai J, Urich T, Schleper C (2013) Responses of the terrestrial ammonia-oxidizing archaeon Ca. Nitrososphaera viennensis and the ammonia-oxidizing bacterium Nitrosospira multiformis to nitrification inhibitors. FEMS Microbiology Letters 344(2):121-129.
  • Eme L, Reigstad L, Spang A, Lanzen A, Weinmaier T, Rattei T, Schleper C, Brochier-Armanet C (2013) Metagenomics of Kamchatkan hot spring filaments reveal two new major (hyper)thermophilic lineages related to Thaumarchaeota. Research in Microbiology 164(5): 425-438.
  • Poulsen M, Schwab C, Jensen B, Engberg R, Spang A, Canibe N, Højberg O, Milinovich G, Fragner L, Schleper C, Weckwerth W, Lund P, Schramm A, Urich T (2013) Methylotrophic methanogenic Thermoplasmata implicated in reduced methane emissions from bovine rumen. nature communications 4: 1428.
  • Vissers E, Anselmetti F, Bodelier P, Muyzer G, Schleper C, Tourna M, Laanbroek H (2013) Temporal and Spatial Coexistence of Archaeal and Bacterial amoA Genes and Gene Transcripts in Lake Lucerne. Archaea-An international Microbiological Journal: 289478.
  • Vissers EW, Blaga CI, Bodelier PL, Muyzer G, Schleper C, Sinninghe Damsté JS, Tourna M, Laanbroek HJ (2013) Seasonal and vertical distribution of putative ammonia-oxidizing thaumarchaeotal communities in an oligotrophic lake. FEMS Microbiology Ecology 83(2): 515-526.


2012

  • Spang A, Poehlein A, Offre P, Zumbrägel S, Haider S, Rychlik N, Nowka B, Schmeisser C, Lebedeva EV, Rattei T, Böhm C, Schmid M, Galushko A, Hatzenpichler R, Weinmaier T, Daniel R, Schleper C, Spieck E, Streit W, Wagner M (2012) The genome of the ammonia-oxidizing Candidatus Nitrosopshaera gargensis: Insights into metabolic versatility and environmental adaptations. Environmental Microbiology 14(12): 3122-3145.
  • Jørgensen S, Hannisdal B, Lanzen A, Baumberger T, Flesland K, Fonseca R, Ovreas L, Steen IH, Torseth IH, Pedersen RB, Schleper C (2012) Correlating microbial community profiles with geochemical data in highly stratified sediments from the Arctic Mid-Ocean Ridge. Proceedings of the National Academy of Sciences 109(42): E2846-E2855.
  • Sinninghe Damsté JS, Rijpstra WI, Hopmans EC, Jung MY, Kim JG, Rhee SK, Stieglmeier M, Schleper C (2012) Intact polar and core glycerol dibiphytanyl glycerol tetraether lipids of group I.1a and I.1b thaumarchaeota in soil. Applied and Environmental Microbiology 78(19): 6866-6874.
  • Bartossek R, Spang A, Weidler G, Lanzen A, Schleper C (2012) Metagenomic analysis of ammonia-oxidizing archaea affiliated with the soil group. Frontiers in Microbiology 3: 208.
  • Berry D, Schwab C, Milinovich G, Reichert J, Ben Mahfoudh K, Decker T, Engel M, Hai B, Hainzl E, Heider S, Kenner L, Müller M, Rauch I, Strobl B, Wagner M, Schleper C, Urich T, Loy A (2012) Phylotype-level 16S rRNA analysis reveals new bacterial indicators of health state in acute murine colitis. ISME Journal 6(11): 2091-2106.
  • Radax R, Rattei T, Lanzen A, Bayer C, Rapp HT, Urich T, Schleper C (2012) Metatranscriptomics of the marine sponge Geodia barretti: tackling phylogeny and function of its microbial community. Environmental Microbiology 14(5): 1308-1324.
  • Radax R, Hoffmann F, Rapp HT, Leininger S, Schleper C (2012) Ammonia-oxidizing archaea as main drivers of nitrification in cold-water sponges. Environmental Microbiology 14(4): 909-923.


2011

  • Ajon M, Fröls S, van Wolferen M, Stoecker K, Teichmann D, Driessen AJM, Grogan DW, Albers SV, Schleper C (2011) UV-inducible DNA exchange in hyperthermophilic archaea mediated by type IV pili. Molecular Microbiology 82(4): 807-817.
  • Reigstad LJ, Jorgensen SL, Lauritzen SE, Schleper C, Urich T (2011) Sulfur-oxidizing chemolithotrophic proteobacteria dominate the microbiota in high arctic thermal springs on svalbard. Astrobiology 11(7): 665-678.
  • Reeve JN, Schleper C (2011) Archaea: very diverse, often different but never bad? Current Opinion in Microbiology 14(3): 271-273.
  • Tourna M, Stieglmeier M, Spang A, Könneke M, Schintlmeister A, Urich T, Engel M, Schloter M, Wagner M, Richter A, Schleper C (2011) Nitrososphaera viennensis, an ammonia oxidizing archaeon from soil. Proceedings of the National Academy of Sciences 108(20): 8420-8425.
  • Reigstad LJ, Bartossek R, Schleper C (2011) Preparation of high-molecular weight DNA and metagenomic libraries from soils and hot springs. Methods in Enzymology 496: 319-344.
  • Manica A, Zebec Z, Teichmann D, Schleper C (2011) In vivo activity of CRISPR-mediated virus defence in a hyperthermophilic archaeon. Molecular Microbiology 80(2): 481-491.
  • Krupovic M, Spang A, Gribaldo S, Forterre P, Schleper C (2011) A thaumarchaeal provirus testifies for an ancient association of tailed viruses with archaea. Biochemical Society Transactions 39(1): 82-88.


2010

  • Schleper C (2010) Ammonia oxidation: different niches for bacteria and archaea? ISME Journal 4(9): 1092-1094.
  • Spang A, Hatzenpichler R, Brochier-Armanet C, Rattei T, Tischler P, Spieck E, Streit W, Stahl DA, Wagner M, Schleper C (2010) Distinct gene set in two different lineages of ammonia-oxidizing archaea supports the phylum Thaumarchaeota. Trends in Microbiology 18(8): 331-340.
  • Bartossek R, Nicol GW, Lanzen A, Klenk HP, Schleper C (2010) Homologues of nitrite reductases in ammonia-oxidizing archaea: diversity and genomic context. Environmental Microbiology 12(4): 1075-1088.
  • Reigstad LH, Jorgensen SL, Schleper C (2010) Diversity and abundance of Korarchaeota in terrestrial hot springs of Iceland and Kamchatka. ISME Journal 4(3): 346-356.


2009

  • Zaparty M, Esser D, Gertig S, Haferkamp P, Kouril T, Manica A, Pham TK, Reimann J, Schreiber K, Sierocinski P, Teichmann D, van Wolferen M, von Jan M, Wieloch P, Albers SV, Driessen AJ, Klenk HP, Schleper C, Schomburg D, van der Oost J, Wright PC, Siebers B (2009) "Hot standards" for the thermoacidophilic archaeon Sulfolobus solfataricus. Extremophiles 14(1): 119-42.
  • Redder P, Peng X, Brügger K, Shah SA, Roesch F, Greve B, She Q, Schleper C, Forterre P, Garrett RA, Prangishvili D (2009) Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism. Environmental Microbiology 11(11): 2849-2862.
  • Hoffmann F, Radax R, Woebken D, Holtappels M, Lavik G, Rapp HT, Schläppy ML, Schleper C, Kuypers MM (2009) Complex nitrogen cycling in the sponge Geodia barretti. Environmental Microbiology 11(9): 2228-2243.
  • Schauss K, Focks A, Leininger S, Kotzerke A, Heuer H, Thiele-Bruhn S, Sharma S, Wilke BM, Matthies M, Smalla K, Munch JC, Amelung W, Kaupenjohann M, Schloter M, Schleper C (2009) Dynamics and functional relevance of ammonia-oxidizing archaea in two agricultural soils. Environmental Microbiology 11(2): 446-56.
  • Albers SV, Birkeland NK, Driessen AJ, Gertig S, Haferkamp P, Klenk HP, Kouril T, Manica A, Pham TK, Ruoff P, Schleper C, Schomburg D, Sharkey KJ, Siebers B, Sierocinski P, Steuer R, van der Oost J, Westerhoff HV, Wieloch P, Wright PC, Zaparty M SulfoSYS (Sulfolobus Systems Biology) (2009) Towards a silicon cell model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation. Biochemical Society Transactions 37(Pt 1):58-64.


2008

  • Schleper C (2008) Microbial ecology: Metabolism of the deep. Nature 456(7223): 712-714.
  • Perevalova AA, Kolganova TV, Birkeland NK, Schleper C, Bonch-Osmolovskaya EA, Lebedinsky AV (2008) Distribution of Crenarchaeota representatives in terrestrial hot springs of Russia and Iceland. Applied and Environmental Microbiology 74(24): 7620-7628.
  • Fröls S, Ajon M, Wagner M, Teichmann D, Zolghadr B, Folea M, Boekema, Driessen AJM, Schleper C , Albers SV (2008) UV-inducible cellular aggregation of the hyperthermophilic archaeon Sulfolobus solfataricus is mediated by pili formation. Molecular Microbiology 70(4): 938-952.
  • Nicol GW, Leininger S, Schleper C, Prosser JI (2008) The influence of soil pH on the diversity, abundance and transcriptional activity of ammonia oxidizing archaea and bacteria. Environmental Microbiology 10(11): 2966-2978.
  • Urich T, Lanzén A, Qi J, Huson DH, Schleper C, Schuster SC (2008) Simultaneous assessment of soil microbial community structure and function through analysis of the meta-transcriptome. PLoS ONE 3(6): e2527.
  • Reigstad LJ, Richter A, Daims H, Urich T, Schwark L, Schleper C (2008) Nitrification in terrestrial hot springs of Iceland and Kamchatka. FEMS Microbiology Ecology 64(2): 167-174.


2007

  • Fröls S, Gordon PM, Panlilio MA, Duggin ID, Bell SD, Sensen CW, Schleper C (2007) Response of the hyperthermophilic Archaeon Sulfolobus solfataricus to UV damage. Journal of Bacteriology 189(23): 8708-8718.
  • Fröls S, Gordon PM, Panlilio MA, Schleper C, Sensen CW (2007) Elucidating the transcription cycle of the UV-inducible hyperthermophilic archaeal virus SSV1 by DNA microarrays. Virology 365(1): 48-59.


2006

  • Hallam S, Mincer T, Schleper C, Preston C, Roberts K, Richardson P, DeLong E (2006) Pathways of carbon assimilation and ammonia oxidation suggested by environmental genomic analyses of marine crenarchaeota. PLOS Biology 4(4): 520-536.
  • Hallam S, Konstantinidis K, Putnam N, Schleper C, Watanabe Y, Sugahara J, Preston C, de la Torre J, Richardson P, DeLong E (2006) Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum symbiosum. Proceedings of the National Academy of Sciences 103(48): 18296-18301.
  • Lubelska J, Jonuscheit M, Schleper C, Albers S, Driessen A (2006) Regulation of expression of the arabinose and glucose transporter genes in the thermophilic archaeon Sulfolobus solfataricus. Extremophiles 10(5): 383-391.
  • Leininger S, Urich T, Schloter M, Schwark L, Qi J, Nicol G, Prosser J, Schuster S, Schleper C (2006) Archaea predominate among ammonia-oxidizing prokaryotes in soils. Nature 442(7104): 806-809.
  • Fieseler L, Quaiser A, Schleper C, Hentschel U (2006) Analysis of the first genome fragment from the marine sponge-associated, novel candidate phylum Poribacteria by environmental genomics. Environmental Microbiology 8(4): 612-624.
  • Albers S, Jonuscheit M, Dinkelaker S, Urich T, Kletzin A, Tampe R, Driessen A, Schleper C (2006) Production of recombinant and tagged proteins in the hyperthermophilic archaeon Sulfolobus solfataricus. Applied and Environmental Microbiology 71(1): 102-111.


2005

  • Treusch A, Leiniger S, Kletzin A, Schuster S, Klenk H, Schleper C (2005) Novel genes for nitrite reductase and Amo-related proteins indicate a role of uncultivated mesophilic crenarchaeota in nitrogen cycling. Environmental Microbiology 7(12): 1985-1995.


2004

  • Treusch A, Kletzin A, Raddatz G, Ochsenreiter T, Quaiser A, Meurer G, Schuster S, Schleper C (2004) Characterization of large-insert DNA libraries from soil for environmental genomic studies of Archaea. Environmental Microbiology 6(9): 970-980.
  • Fuetterer O, Angelov A, Liesegang H, Gottschalk G, Schleper C, Schepers B, Dock C, Antranikian G, Liebl W (2004) Genome sequence of Picrophilus torridus and its implications for life around pH 0. Proceedings of the National Academy of Sciences 101(24): 9091-9096.


2003

  • Quaiser A, Ochsenreiter T, Lanz C, Schuster S, Treusch A, Eck J, Schleper C (2003) Acidobacteria form a coherent but highly diverse group within the bacterial domain: evidence from environmental genomics. Molecular Microbiology 50(2): 563-575.
  • Ochsenreiter T, Selezi D, Quaiser A, Bonch-Osmolovskaya L, Schleper C (2003) Diversity and abundance of Crenarchaeota in terrestrial habitats studied by 16S RNA surveys and real time PCR. Environmental Microbiology 5(9): 787-797.
  • Jonuscheit M, Martusewitsch E, Stedman K, Schleper C (2003) A reporter gene system for the hyperthermophilic archaeon Sulfolobus solfataricus based on a selectable and integrative shuttle vector. Molecular Microbiology 48(5): 1241-1252.
  • Lorenz P, Liebeton K, Niehaus F, Schleper C, Eck J (2003) The impact of non-cultivated biodiversity on enzyme discovery and evolution. Biocatalysis and Biotransformation 21(2): 87-91.


2002

  • Quaiser A, Ochsenreiter T, Klenk H, Kletzin A, Treusch A, Meurer G, Eck J, Sensen C, Schleper C (2002) First insight into the genome of an uncultivated crenarchaeote from soil. Environmental Microbiology 4(10): 603-611.
  • Ochsenreiter T, Pfeifer F, Schleper C (2002) Diversity of Archaea in hypersaline environments characterized by molecular-phylogenetic and cultivation studies. Extremophiles 6(4): 267-274.


2001

  • Rahmati S, Ronco F, Spittle M, Morris A, Schleper C, Rosales L, Kaufman A, Amerling R, Ronco C, Levin N (2001) Validation of the blood temperature monitor for extracorporeal thermal energy balance during in vitro continuous hemodialysis. Blood Purification 19(2): 245-250.


2000

  • Martusewitsch E, Sensen C, Schleper C (2000) High spontaneous mutation rate in the hyperthermophilic archaeon Sulfolobus solfataricus is mediated by transposable elements. Journal of Bacteriology 182(9):2 574-2581.


1999

  • Stedman K, Schleper C, Rumpf E, Zillig W (1999) Genetic requirements for the function of the archaeal virus SSV1 in Sulfolobus solfataricus: Construction and testing of viral shuttle vectors. Genetics 152(4): 1397-1405.
  • DeLong E, Schleper C, Feldman R, Swanson R (1999) Application of genomics for understanding the evolution of hyperthermophilic and nonthermophilic Crenarchaeota. Biological Bulletin 196(3): 363-365.
  • Sandler S, Hugenholtz P, Schleper C, DeLong E, Pace N, Clark A (1999) Diversity of radA genes from cultured and uncultured Archaea: Comparative analysis of putative RadA proteins and their use as a phylogenetic marker. Journal of Bacteriology 181(3): 907-915.


1998

  • Schleper C, DeLong E, Preston C, Feldman R, Wu K, Swanson R (1998) Genomic analysis reveals chromosomal variation in natural populations of the uncultured psychrophilic archaeon Cenarchaeum symbiosum. Journal of Bacteriology 180(19): 5003-5009.
  • DeLong E, King L, Massana R, Cittone H, Murray A, Schleper C, Wakeham S (1998) Dibiphytanyl ether lipids in nonthermophilic crenarchaeotes. Applied and Environmental Microbiology 64(3): 1133-1138.


1997

  • Schleper C, Swanson R, Mathur E, DeLong E (1997) Characterization of a DNA polymerase from the uncultivated psychrophilic archaeon Cenarchaeum symbiosum. Journal of Bacteriology 179(24):7803-7811.
  • Schleper C, Holben W, Klenk H (1997) Recovery of Crenarchaeotal ribosomal DNA sequences from freshwater-lake sediments. Applied and Environmental Microbiology 63(1): 321-323.


1996

  • Schleper C, Puhler G, Klenk H, Zillig W (1996) Picrophilus oshimae and Picrophilus torridus fam nov, gen nov, sp nov, two species of hyperacidophilic, thermophilic, heterotrophic, aerobic archaea. International Journal of Systematic Bacteriology 46(3): 814-816.
  • Elferink M, Schleper C, Zillig W (1996) Transformation of the extremely thermoacidophilic archaeon Sulfolobus solfataricus via a self-spreading vector. FEMS Microbiology Letters 137(1): 31-35.
  • Keeling P, Klenk H, Singh R, Feeley O, Schleper C, Zillig W, Doolittle W, Sensen C (1996) Complete nucleotide sequence of the Sulfolobus islandicus multicopy plasmid pRN1. Plasmid 35(2): 141-144.


1995

  • Schleper C, Puehler G, Holz I, Gambacorta A, Janekovic D, Santarius U, Klenk H, Zillig W (1995) Picrophilus gen-nov, fam-nov - A Novel aerobic heterotrophic, thermoacidophilic genus and family comprising archaea capable of growth around pH-0. Journal of Bacteriology 177(24): 7050-7059.
  • Schleper C, Holz I, Janekovic D, Murphy J, Zillig (1995) A multicopy plasmid of the extremely thermophilic archaeon Sulfolobus effects its transfer to Recipients by Mating. Journal of Bacteriology 177(15): 4417-4426.
  • Schleper C, Puhler G, Kuhlmorgen B, Zillig W (1995) Life at extremely low pH. Nature 375(6534): 741-742.


1994

  • Schleper C, Roder R, Singer T, Zillig W (1994) An insertion element of the extremely thermophilic archaeon Sulfolobus solfataricus transposes into the endogenous Beta-Galactosidase Gene. Molecular & General Genetics 243(1): 91-96.
  • Zillig W, Kletzin A, Schleper C, Holz I, Janekovic D, Hain J, Lanzendorfer M, Kristjansson J (1994) Screening for Sulfolobales, their Plasmids and their Viruses in Icelandic Solfataras. Systematic and Applied Microbiology 16(4): 609-628.
  • Durovic P, Kutay U, Schleper C, Dennis P (1994) Strain Identification and 5S Ribosomal-RNA Gene Characterization of the Hyperthermophilic Archaeabacterium Sulfolobus acidocaldarius. Journal of Bacteriology 176(2): 514-517.


1993

  • Palm P, Schleper C, Arnoldammer I, Holz I, Meier T, Lottspeich F, Zillig W (1993) The DNA-dependent RNA-Polymerase of Thermotoga maritima - Characterization of the enzyme and the DNA-sequence of the genes for the large subunits. Nucleic acids Research 21(21): 4904-4908.
  • Klenk H, Schleper C, Schwass V, Brudler R (1993) Nucleotide sequence, transcription and phylogeny of the gene encoding the superoxide-dismutase of Sulfolobus acidocaldarius. Biochimica et Biophysica Acta 1174(1): 95-98.


1992

  • Schleper C, Kubo K, Zillig W (1992) The Particle SSV1 from the extremely thermophilic Archaeon Sulfolobus is a virus - demonstration of infectivity and of transfection with viral-DNA. Proceedings of the National Academy of Sciences 89(16): 7645-7649.


1991

  • Palm P, Schleper C, Grampp B, Yeats S, McWilliam P, Reiter W, Zillig W (1991) Complete Nucleotide sequence of the virus SSV1 of the Archaebacterium Sulfolobus shibatae. Virology 185(1): 242-250.


BOOK CHAPTERS AND OTHER

  • Stieglmeier M, Alves R, Schleper C (2014) Thaumarchaeota. In: Prokaryotes- Other Major Lineages of Bacteria and The Archaea. Rosenberg, E., DeLong E.F., Lory, S., Stackebrandt, E., Thompson F. (Eds.) 4th ed. 2014 Springer.
  • Albers SV, Forterre P, Pranighvili D, Schleper C (2013) The legacy of Carl Woese and Wolfram Zillig: from phylogeny to landmark discoveries. Nature Reviews Microbiology 11: 713-719.
  • Offre P, Spang A, Schleper C (2013) Archaea in Biogeochemical Cycles. Annual Review of Microbiology 67: 437-457.
  • Manica A, Schleper C (2013) CRISPR-mediated defense mechanisms in the hyperthermophilic archaeal genus Sulfolobus. Biology 10(5): 671-678.
  • Pester M, Schleper C, Wagner M (2011) The Thaumarchaeota: an emerging view of their phylogeny and ecophysiology. Current Opinion in Microbiology 14(3): 300-306.
  • Urich T, Schleper C (2011) The "double RNA" approach to simultaneously assess the structure and function of environmental microbial communities by meta-transcriptomics. In: Handbook of Molecular Microbial Ecology I: Metagenomics and Complementary Approaches. Wiley-Blackwell. de Bruijn F (ed).
  • Schleper C, Nicol GW (2010) Ammonia-oxidising archaea-physiology, ecology and evolution. Advances in Microbial Physiology 57: 1-47.
  • Nicol G, Leininger S, Schleper C (2010) Distribution and Activity of Ammonia-oxidizing Archaea in Natural Environments. In Nitrification. American Society of Microbiology Washington DC, USA. Ward B, Arp D, Klotz M (eds) pp. 157-178.
  • Fröls S, White MF, Schleper C (2009) Reactions to UV damage in the model archaeon solfataricus. Biochemical Society Transactions 37: 36-41.
  • Schleper C (2007) Diversity and Ecology of Archaea: Perspectives from microbial ecology and metagenomics. In: Archaea: Evolution, Physiology & Molecular Biology. Blackwell Publishing. Klenk H, R Garrett R (eds) pp. 39-50.
  • Nicol G, Schleper C (2006) Ammonia-oxidising Crenarchaeota: important players in the nitrogen cycle? Trends in Microbiology 14(5): 207-212.
  • Treusch A, Schleper C (2006) The microbial soil flora: Novel approaches for accessing the phylogenetic and physiological diversity of prokaryotes. In: Soil Biology: Intestinal Microorganisms of Termites and other Invertebrates. Springer Verlag Berlin, Deutschland. Konig H, Varma A (eds) pp. 407-424.
  • Treusch A, Schleper C (2005) Environmental Genomics: A Novel Tool for Study of Uncultivated Microorganisms. in: Handbook of Genome Research: Genomics, Proteomics, Metabolomics, Bioinformatics, Ethical and Legal Issues. Blackwell Science Publication, Osney Mead, Oxford, England. Sensen C (ed) pp. 45-57.
  • Schleper C, Jurgens G, Jonuscheit M (2005) Genomic studies of uncultivated archaea. Nature Reviews Microbiology 3(6): 479-488.
  • Lorenz P, Schleper C (2002) Metagenome - a challenging source of enzyme discovery. Journal of Molecular Catalysis B-Enzymatic 19(SI): 13-19.
  • Schulze R, Meurer G, Schleper C (2002) Das Metagenom als Quelle neuartiger, rekombinanter Wirkstoffe und Enzyme. BIOspektrum-Sonderausgabe (8): 498-501.
  • Schleper C, Eck J (2000) Umweltgenomik: Charakterisierung und Nutzung nicht-kultivierter Mikroorganismen. BIOspektrum 6:449-451.
  • Schleper C (1999) The archaebacteria among us. La Recherche-Spécial: Les Frontières du Vivant. 317:30-33.
  • Zillig W, Prangishvilli D, Schleper C, Elferink M, Holz I, Albers S, Janekovic D, Gotz D (1996) Viruses, plasmids and other genetic elements of thermophilic and hyperthermophilic Archaea. FEMS Microbiology Reviews 18(2-3): 225-236.
  • Schleper C, Zillig W (1995) Transfection of Sulfolobus solfataricus. In: Archaea: Thermophiles: A laboratory manual. Cold Spring Harbor Laboratory Press, New York, USA. Robb F, Place A (eds) pp. 91-93.
  • Zillig W, Palm P, Klenk HP, Pühler G, Gropp F, Schleper C (1991) Phylogeny of DNA-dependent RNA-polymerases: Testimony for the origin of eukaryotes. In: General and Applied Aspects of Halophilic Microorganisms. NATO ASI Series 201. Plenum Press, New York. Rodriguez-Valera F (ed.) pp. 321-332.

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